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1.B.6.1.2
OmpF (OprF) porin.  The N-terminal domain has pore activity (Saint et al. 2000).  The protein can exist in multiple conformations of variable conductivity (Nestorovich et al. 2006).  Factors affecting the folding of Pseudomonas aeruginosa OprF porin into the one-domain open conformer have been studied by Sugawara et al. (2010). OprF is a complement component C3 receptor (Mishra et al. 2015).

Accession Number:P13794
Protein Name:PORF aka OmpF aka OprF aka PA1777
Length:350
Molecular Weight:37640.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

HEGENOM: HBG730341
RefSeq: NP_250468.1   
Entrez Gene ID: 878442   
Pfam: PF00691    PF05736   
BioCyc: PAER208964:PA1777-MONOMER   
KEGG: pae:PA1777   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0006811 P:ion transport
GO:0008360 P:regulation of cell shape

References (2)

[1] “Sequence and transcriptional start site of the Pseudomonas aeruginosa outer membrane porin protein F gene.”  Duchene M.et.al.   2447060
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
Structure:
4RLC     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKLKNTLGVV IGSLVAASAM NAFAQGQNSV EIEAFGKRYF TDSVRNMKNA DLYGGSIGYF 
61:	LTDDVELALS YGEYHDVRGT YETGNKKVHG NLTSLDAIYH FGTPGVGLRP YVSAGLAHQN 
121:	ITNINSDSQG RQQMTMANIG AGLKYYFTEN FFAKASLDGQ YGLEKRDNGH QGEWMAGLGV 
181:	GFNFGGSKAA PAPEPVADVC SDSDNDGVCD NVDKCPDTPA NVTVDANGCP AVAEVVRVQL 
241:	DVKFDFDKSK VKENSYADIK NLADFMKQYP STSTTVEGHT DSVGTDAYNQ KLSERRANAV 
301:	RDVLVNEYGV EGGRVNAVGY GESRPVADNA TAEGRAINRR VEAEVEAEAK