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Accession Number: | P13128 |
Protein Name: | TACY aka HLY aka LISA aka HLYA aka LMO0202 |
Length: | 529 |
Molecular Weight: | 58688.00 |
Species: | Listeria monocytogenes [1639] |
Location1 / Topology2 / Orientation3: | Secreted1 |
Substrate | molecule |
Cross database links:
RefSeq: | NP_463733.1 |
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Entrez Gene ID: | 987033 |
Pfam: | PF01289 |
BioCyc: | LMON169963:LMO0202-MONOMER |
KEGG: | lmo:lmo0202 |
Gene Ontology
GO:0015485
F:cholesterol binding
GO:0019835
P:cytolysis
GO:0019836
P:hemolysis by symbiont of host erythrocytes
GO:0009405
P:pathogenesis
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References (7)[1] “Nucleotide sequence of the listeriolysin gene from a Listeria monocytogenes serotype 1/2a strain.” Domann E.et.al. 2505236 [2] “Expression in Escherichia coli and sequence analysis of the listeriolysin O determinant of Listeria monocytogenes.” Mengaud J.et.al. 3126142 [3] “Listeria monocytogenes isolates can be classified into two major types according to the sequence of the listeriolysin gene.” Rasmussen O.F.et.al. 1937753 [4] “Identification and characterization of nucleotide sequence differences in three virulence-associated genes of Listeria monocytogenes strains representing clinically important serotypes.” Vines A.et.al. 9541569 [5] “Comparative genomics of Listeria species.” Glaser P.et.al. 11679669 [6] “Identification of the structural gene encoding the SH-activated hemolysin of Listeria monocytogenes: listeriolysin O is homologous to streptolysin O and pneumolysin.” Mengaud J.et.al. 2824384 [7] “Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O.” Michel E.et.al. 1965218
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MKKIMLVFIT LILVSLPIAQ QTEAKDASAF NKENSISSMA PPASPPASPK TPIEKKHADE 61: IDKYIQGLDY NKNNVLVYHG DAVTNVPPRK GYKDGNEYIV VEKKKKSINQ NNADIQVVNA 121: ISSLTYPGAL VKANSELVEN QPDVLPVKRD SLTLSIDLPG MTNQDNKIVV KNATKSNVNN 181: AVNTLVERWN EKYAQAYPNV SAKIDYDDEM AYSESQLIAK FGTAFKAVNN SLNVNFGAIS 241: EGKMQEEVIS FKQIYYNVNV NEPTRPSRFF GKAVTKEQLQ ALGVNAENPP AYISSVAYGR 301: QVYLKLSTNS HSTKVKAAFD AAVSGKSVSG DVELTNIIKN SSFKAVIYGG SAKDEVQIID 361: GNLGDLRDIL KKGATFNRET PGVPIAYTTN FLKDNELAVI KNNSEYIETT SKAYTDGKIN 421: IDHSGGYVAQ FNISWDEVNY DPEGNEIVQH KNWSENNKSK LAHFTSSIYL PGNARNINVY 481: AKECTGLAWE WWRTVIDDRN LPLVKNRNIS IWGTTLYPKY SNKVDNPIE