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1.C.24.1.6
Class IIa bacteriocin Leucocin A precursor

Accession Number:P34034
Protein Name:LCCA aka LCNA
Length:61
Molecular Weight:6586.00
Species:Leuconostoc gelidum [1244]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, electrolytes, water

Cross database links:

Pfam: PF01721   

Gene Ontology

GO:0005576 C:extracellular region
GO:0005102 F:receptor binding
GO:0019835 P:cytolysis
GO:0042742 P:defense response to bacterium

References (3)

[1] “Characterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum.”  Hastings J.W.et.al.   1840587
[2] “15N- and 13C-labeled media from Anabaena sp. for universal isotopic labeling of bacteriocins: NMR resonance assignments of leucocin A from Leuconostoc gelidum and nisin A from Lactococcus lactis.”  Sailer M.et.al.   8418850
[3] “Three-dimensional structure of leucocin A in trifluoroethanol and dodecylphosphocholine micelles: spatial location of residues critical for biological activity in type IIa bacteriocins from lactic acid bacteria.”  Gallagher N.L.F.et.al.   9398233
Structure:
1CW6   2LEU   3LEU   2LJQ   2LJT     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MMNMKPTESY EQLDNSALEQ VVGGKYYGNG VHCTKSGCSV NWGEAFSAGV HRLANGGNGF 
61:	W