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1.C.42.1.2
C2II channel-forming toxin component.  Channel-formation is inhibited by azolopyridinium salts (Bronnhuber et al. 2014).

Accession Number:O86171
Protein Name:C2 toxin (Component-II)
Length:721
Molecular Weight:80516.00
Species: [1491]
Location1 / Topology2 / Orientation3: Secreted1
Substrate Protein toxins, small molecules

Cross database links:

Pfam: PF03495   

Gene Ontology

GO:0005576 C:extracellular region
GO:0009405 P:pathogenesis

References (2)

[1] “Characterization of component-I gene of botulinum C2 toxin and PCR detection of its gene in clostridial species.”  Fujii N.et.al.   8645309
[2] “The gene for component-II of botulinum C2 toxin.”  Kimura K.et.al.   9659689
Structure:
2J42     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLVSKFENSV KNSNKNYFTI NGLMGYYFEN DFFNLNIISP TLDGNLTFSK EDINSILGNK 
61:	IIKSARWIGL IKPSITGEYI LSTNSPNCRV ELNGEIFNLS LNTSNTVNLI QGNVYDIRIE 
121:	QLMSENQLLK NYEGIKLYWE TSDIIKEIIP SEVLLKPNYS NTNEKSKFIP NNTLFSNAKL 
181:	KANANRDTDR DGIPDEWEIN GYTVMNQKAV AWDDKFAANG YKKYVSNPFK PCTANDPYTD 
241:	FEKVSGQIDP SVSMVARDPM ISAYPIVGVQ MERLVVSKSE TITGDSTKSM SKSTSHSSTN 
301:	INTVGAEVSG SLQLAGGIFP VFSMSASANY SHTWQNTSTV DDTTGESFSQ GLSINTGESA 
361:	YINPNIRYYN TGTAPVYNVT PTTTIVIDKQ SVATIKGQES LIGDYLNPGG TYPIIGEPPM 
421:	ALNTMDQFSS RLIPINYNQL KSIDNGGTVM LSTSQFTGNF AKYNSNGNLV TDGNNWGPYL 
481:	GTIKSTTASL TLSFSGQTTQ VAVVAPNFSD PEDKTPKLTL EQALVKAFAL EKKNGKFYFH 
541:	GLEISKNEKI QVFLDSNTNN DFENQLKNTA DKDIMHCIIK RNMNILVKVI TFKENISSIN 
601:	IINDTNFGVQ SMTGLSNRSK GQDGIYRAAT TAFSFKSKEL KYPEGRYRMR FVIQSYEPFT 
661:	CNFKLFNNLI YSSSFDKGYY DEFFYFYYNG SKSFFNISCD IINSINRLSG VFLIELDKLI 
721:	I