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1.C.47.1.3
Sapecin precursor

Accession Number:P18313
Protein Name:SAPE
Length:94
Molecular Weight:9915.00
Species:Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) [7386]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, ions

Cross database links:

Pfam: PF01097   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042742 P:defense response to bacterium
GO:0045087 P:innate immune response

References (4)

[1] “Molecular cloning of cDNA for sapecin and unique expression of the sapecin gene during the development of Sarcophaga peregrina.”  Matsuyama K.et.al.   3182837
[2] “Purification of three antibacterial proteins from the culture medium of NIH-Sape-4, an embryonic cell line of Sarcophaga peregrina.”  Matsuyama K.et.al.   3182836
[3] “Determination of the disulfide array in sapecin, an antibacterial peptide of Sarcophaga peregrina (flesh fly).”  Kuzuhara T.et.al.   2358424
[4] “1H nuclear magnetic resonance study of the solution conformation of an antibacterial protein, sapecin.”  Hanzawa H.et.al.   2401368
Structure:
1L4V     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKSFIVLAVT LCLAAFFMGQ SVASPAAAAE ESKFVDGLHA LKTIEPELHG RYKRATCDLL 
61:	SGTGINHSAC AAHCLLRGNR GGYCNGKAVC VCRN