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1.C.59.2.1
Neurotoxin

Accession Number:P46085
Protein Name:HA-70 or ANTP-70
Length:623
Molecular Weight:70650.00
Species:Clostridium botulinum [1491]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules

Cross database links:

Pfam: PF03505   

Gene Ontology

GO:0005576 C:extracellular region
GO:0009405 P:pathogenesis

References (2)

[1] “Molecular construction of Clostridium botulinum type C progenitor toxin and its gene organization.”  Fujinaga Y.et.al.   7802661
[2] “Organization of the botulinum neurotoxin C1 gene and its associated non-toxic protein genes in Clostridium botulinum C 468.”  Hauser D.F.et.al.   8028579
Structure:
2ZOE   2ZS6   4EN6   4EN7   4EN8   4EN9     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSLSIKELYY TKDKSINNVN LADGNYVVNR GDGWILSRQN QNLGGNISNN GCTAIVGDLR 
61:	IRETATPYYY PTASFNEEYI KNNVQNVFAN FTEASEIPIG FEFSKTAPSN KSLYMYLQYT 
121:	YIRYEIIKVL QNTVTERAVL YVPSLGYVKS IEFNSEEQID KNFYFTSQDK CILNEKFIYK 
181:	KIDDTITVKE SKNSNNNINF NTSQTILPYP NGLYVINKGD GYMRTNDKDL IGTLLIESST 
241:	SGSIIQPRLR NTTRPLFNTS NPTIFSQEYT EARLNDAFNI QLFNTSTTLF KFVEEAPTNK 
301:	NISMKVYNTY EKYELINYQN GNIDDKAEYY LPSLGKCEVS DAPSPQAPVV ETPVDQDGFI 
361:	QTGPNENIIV GVINPSENIE EISTPIPDDY TYNIPTSIQN NACYVLFKVN TTGVYKITTK 
421:	NNLPPLIIYE AIGSSNRNMN SNNLSNDNIK AIKYITGLNR SDAKSYLIVS LFKDKNYYIR 
481:	IPQISSSTTS QLIFKRELGN ISDLADSTVN ILDNLNTSGT HYYTRQSPDV GNYISYQLTI 
541:	PGDFNNIASS IFSFRTRNNQ GIGTLYRLTE SINGYNLITI NNYSDLLNNV EPISLLNGAT 
601:	YIFRVKVTEL NNYNIIFDAY RNS