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1.C.71.1.2 The Cyt2Aa δ endotoxin of 259 aas. Cyt2Aa2 binds and aggregates on the lipid membrane leading to the formation of non-specific holes and disruption of the cell membrane (Tharad et al. 2016). The crystal structure is available (PDB 3RON).
Accession Number:	Q04470
Protein Name:	Cyt2Aa aka CytB
Length:	259
Molecular Weight:	29235.00
Species:	Bacillus thuringiensis (subsp. kyushuensis) [44161]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate	cation

Structure:
Pfam:	PF01338
Gene Ontology GO:0005576 C:extracellular region GO:0042243 P:asexual spore wall assembly GO:0009405 P:pathogenesis
References (2) [1] “Cloning and characterization of a novel Bacillus thuringiensis cytolytic delta-endotoxin.” Koni P.A.et.al. 8429550 [2] “Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation.” Li J.et.al. 8632451
1CBY

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MYTKNFSNSR MEVKGNNGCS APIIRKPFKH IVLTVPSSDL DNFNTVFYVQ PQYINQALHL 
61:	ANAFQGAIDP LNLNFNFEKA LQIANGIPNS AIVKTLNQSV IQQTVEISVM VEQLKKIIQE 
121:	VLGLVINSTS FWNSVEATIK GTFTNLDTQI DEAWIFWHSL SAHNTSYYYN ILFSIQNEDT 
181:	GAVMAVLPLA FEVSVDVEKQ KVLFFTIKDS ARYEVKMKAL TLVQALHSSN APIVDIFNVN 
241:	NYNLYHSNHK IIQNLNLSN

1.C.71.1.2
The Cyt2Aa δ endotoxin of 259 aas. Cyt2Aa2 binds and aggregates on the lipid membrane leading to the formation of non-specific holes and disruption of the cell membrane (Tharad et al. 2016). The crystal structure is available (PDB 3RON).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.C.71.1.2The Cyt2Aa δ endotoxin of 259 aas. Cyt2Aa2 binds and aggregates on the lipid membrane leading to the formation of non-specific holes and disruption of the cell membrane (Tharad et al. 2016). The crystal structure is available (PDB 3RON).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.C.71.1.2
The Cyt2Aa δ endotoxin of 259 aas. Cyt2Aa2 binds and aggregates on the lipid membrane leading to the formation of non-specific holes and disruption of the cell membrane (Tharad et al. 2016). The crystal structure is available (PDB 3RON).