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1.C.71.1.2
The Cyt2Aa δ endotoxin of 259 aas.  Cyt2Aa2 binds and aggregates on the lipid membrane leading to the formation of non-specific holes and disruption of the cell membrane (Tharad et al. 2016). The crystal structure is available (PDB 3RON).

Accession Number:Q04470
Protein Name:Cyt2Aa aka CytB
Length:259
Molecular Weight:29235.00
Species:Bacillus thuringiensis (subsp. kyushuensis) [44161]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate cations

Cross database links:

Pfam: PF01338   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042243 P:asexual spore wall assembly
GO:0009405 P:pathogenesis

References (2)

[1] “Cloning and characterization of a novel Bacillus thuringiensis cytolytic delta-endotoxin.”  Koni P.A.et.al.   8429550
[2] “Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation.”  Li J.et.al.   8632451
Structure:
1CBY     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MYTKNFSNSR MEVKGNNGCS APIIRKPFKH IVLTVPSSDL DNFNTVFYVQ PQYINQALHL 
61:	ANAFQGAIDP LNLNFNFEKA LQIANGIPNS AIVKTLNQSV IQQTVEISVM VEQLKKIIQE 
121:	VLGLVINSTS FWNSVEATIK GTFTNLDTQI DEAWIFWHSL SAHNTSYYYN ILFSIQNEDT 
181:	GAVMAVLPLA FEVSVDVEKQ KVLFFTIKDS ARYEVKMKAL TLVQALHSSN APIVDIFNVN 
241:	NYNLYHSNHK IIQNLNLSN