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2.A.28.2.4
Na+:bile acid symporter (AstB). The 3-d structure is available (3ZUX).

Accession Number:Q9K0A9
Protein Name:Transporter
Length:315
Molecular Weight:32937.00
Species:Neisseria meningitidis serogroup B [491]
Number of TMSs:10
Substrate bile acids, Na+

Cross database links:

HEGENOM: HBG747007
Entrez Gene ID: 902817   
Pfam: PF01758   
KEGG: nme:NMB0705   

Gene Ontology

GO:0016020 C:membrane
GO:0008508 F:bile acid:sodium symporter activity

References (2)

[1] “Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.”  Tettelin H.et.al.   10710307
[2] “Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.”  Hu N.J.et.al.   21976025
Structure:
3ZUX   3ZUY     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNILSKISSF IGKTFSLWAA LFAAAAFFAP DTFKWAGPYI PWLLGIIMFG MGLTLKPSDF 
61:	DILFKHPKVV IIGVIAQFAI MPATAWLLSK LLNLPAEIAV GVILVGCCPG GTASNVMTYL 
121:	ARGNVALSVA VTSVSTLISP LLTPAIFLML AGEMLEIQAA GMLMSIVKMV LLPIVLGLIV 
181:	HKVLGSKTEK LTDALPLVSV AAIVLIIGAV VGASKGKIME SGLLIFAVVV LHNGIGYLLG 
241:	FFAAKWTGLP YDAQKTLTIE VGMQNSGLAA ALAAAHFAAA PVVAVPGALF SVWHNISGSL 
301:	LATYWAAKAG KHKKP