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|---|---|
| Accession Number: | Q42524 |
| Protein Name: | 4-coumarate--CoA ligase 1 |
| Length: | 561 |
| Molecular Weight: | 61053.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | fatty acid |
Cross database links:
| RefSeq: | NP_175579.1 NP_849793.1 |
|---|---|
| Entrez Gene ID: | 841593 |
| Pfam: | PF00501 |
| BioCyc: | MetaCyc:AT1G51680-MONOMER |
Gene Ontology
GO:0016207
F:4-coumarate-CoA ligase activity
GO:0005524
F:ATP binding
GO:0009698
P:phenylpropanoid metabolic process
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References (9)[1] “The Arabidopsis thaliana 4-coumarate:CoA ligase (4CL) gene: stress and developmentally regulated expression and nucleotide sequence of its cDNA.” Lee D.et.al. 7640359 [2] “Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.” Ehlting J.et.al. 10417722 [3] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.” Theologis A.et.al. 11130712 [4] “Empirical analysis of transcriptional activity in the Arabidopsis genome.” Yamada K.et.al. 14593172 [5] “Identification of 4-coumarate:coenzyme A ligase (4CL) substrate recognition domains.” Ehlting J.et.al. 11576429 [6] “Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme a synthetases.” Shockey J.M.et.al. 12805634 [7] “The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase.” Schneider K.et.al. 12819348 [8] “A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic acid.” Schneider K.et.al. 15677481 [9] “Multiple cis-regulatory elements regulate distinct and complex patterns of developmental and wound-induced expression of Arabidopsis thaliana 4CL gene family members.” Soltani B.M.et.al. 16738863
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| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAPQEQAVSQ VMEKQSNNNN SDVIFRSKLP DIYIPNHLSL HDYIFQNISE FATKPCLING 61: PTGHVYTYSD VHVISRQIAA NFHKLGVNQN DVVMLLLPNC PEFVLSFLAA SFRGATATAA 121: NPFFTPAEIA KQAKASNTKL IITEARYVDK IKPLQNDDGV VIVCIDDNES VPIPEGCLRF 181: TELTQSTTEA SEVIDSVEIS PDDVVALPYS SGTTGLPKGV MLTHKGLVTS VAQQVDGENP 241: NLYFHSDDVI LCVLPMFHIY ALNSIMLCGL RVGAAILIMP KFEINLLLEL IQRCKVTVAP 301: MVPPIVLAIA KSSETEKYDL SSIRVVKSGA APLGKELEDA VNAKFPNAKL GQGYGMTEAG 361: PVLAMSLGFA KEPFPVKSGA CGTVVRNAEM KIVDPDTGDS LSRNQPGEIC IRGHQIMKGY 421: LNNPAATAET IDKDGWLHTG DIGLIDDDDE LFIVDRLKEL IKYKGFQVAP AELEALLIGH 481: PDITDVAVVA MKEEAAGEVP VAFVVKSKDS ELSEDDVKQF VSKQVVFYKR INKVFFTESI 541: PKAPSGKILR KDLRAKLANG L