8.B.32.1.10
Alpha-conotoxin PIVA of 68 aas and 1 N-terminal TMS. This α-conotoxin acts on postsynaptic membranes, binding to nicotinic acetylcholine receptors (nAChR) and
inhibiting them. This toxin has higher affinity for the adult subtype
(alpha-1/beta-1/gamma/delta subunits) of the receptor than for the fetal subtype (alpha-1/beta-1/epsilon/delta subunits) (Teichert et al. 2006).
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| Accession Number: | P55963 |
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| Protein Name: | Alpha-conotoxin PIVA |
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| Length: | 68 |
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| Molecular Weight: | 7386.00 |
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| Species: | Conus purpurascens (Purple cone) [41690] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MFTVFLLVVL ATTVVSFTSD RASDDRNTND KASRLLSHVV RGCCGSYPNA ACHPCSCKDR
61: PSYCGQGR