9.B.208.1.4
Nuclear receptor subfamily 5 group A member 2 of 541 aas. It functions as a key regulator of cholesterol 7-alpha-hydroxylase
gene (CYP7A) expression in liver and may also contribute to the regulation
of pancreas-specific genes while playing important roles in embryonic
development (Wang et al. 2005).
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| Accession Number: | O00482 |
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| Protein Name: | Nuclear receptor subfamily 5 group A member 2 |
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| Length: | 541 |
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| Molecular Weight: | 61331.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Nucleus1 |
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| Substrate |
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1: MSSNSDTGDL QESLKHGLTP IGAGLPDRHG SPIPARGRLV MLPKVETEAL GLARSHGEQG
61: QMPENMQVSQ FKMVNYSYDE DLEELCPVCG DKVSGYHYGL LTCESCKGFF KRTVQNNKRY
121: TCIENQNCQI DKTQRKRCPY CRFQKCLSVG MKLEAVRADR MRGGRNKFGP MYKRDRALKQ
181: QKKALIRANG LKLEAMSQVI QAMPSDLTIS SAIQNIHSAS KGLPLNHAAL PPTDYDRSPF
241: VTSPISMTMP PHGSLQGYQT YGHFPSRAIK SEYPDPYTSS PESIMGYSYM DSYQTSSPAS
301: IPHLILELLK CEPDEPQVQA KIMAYLQQEQ ANRSKHEKLS TFGLMCKMAD QTLFSIVEWA
361: RSSIFFRELK VDDQMKLLQN CWSELLILDH IYRQVVHGKE GSIFLVTGQQ VDYSIIASQA
421: GATLNNLMSH AQELVAKLRS LQFDQREFVC LKFLVLFSLD VKNLENFQLV EGVQEQVNAA
481: LLDYTMCNYP QQTEKFGQLL LRLPEIRAIS MQAEEYLYYK HLNGDVPYNN LLIEMLHAKR
541: A