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1.A.1.19.3 Alkalinization-activated, Ca²⁺-selective cation channel of sperm 1, CatSper1, required for male fertility and the hyperactivated motility of spermatozoa. These channels require auxiliary subunits, CatSper β, γ and δ for activity (Chung et al., 2011; Liu et al., 2007).
Accession Number:	A2RTF1
Protein Name:	Cation channel sperm-associated protein subunit beta
Length:	1109
Molecular Weight:	126108.00
Species:	[10090]
Number of TMSs:	3
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	calcium(2+)

RefSeq:	NP_766611.2
Entrez Gene ID:	271036
KEGG:	mmu:271036
Gene Ontology GO:0019861 C:flagellum GO:0016021 C:integral to membrane GO:0005515 F:protein binding GO:0030154 P:cell differentiation GO:0007275 P:multicellular organismal development GO:0007283 P:spermatogenesis
References (4) [1] “CatSperbeta, a novel transmembrane protein in the CatSper channel complex.” Liu J.et.al. 17478420 [2] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein.” Wang H.et.al. 19516020

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MESPLIYVML VLLNVFVFSS GVIHNKGKER TYFSCSGEGI LTGLHTIKLF LTMDNLKVRC 
61:	FFRNENQSPS KEILGLFTSG GLAPNMIITN STFYGGYYFK LTPFSNRLEW LIDIPRQNIT 
121:	VNTDIAAVEQ WMIKITMHEG LNIYDTEGTL LDLVREPILQ WNLGRVLTEM EVRDLYPEVN 
181:	DIKVTKSPCA NDVALIGFMM KPSSNGVFIG KTISGFWTYK ECIWHDLTEI IYAELKDEHQ 
241:	GLTVIDLVLT NHFLVILTSL GLYVSSDLRY PTTSQIKLSR AEFCGFERVD YIRGNLWYNE 
301:	KCFANRESFE VDYVTITFNR NRTLSESSSC FFSKEPFLHW LPCVFSTIKN EKSIPRVITF 
361:	LIDQETDSGI YLFNVQDTKE TYVTVAMLKD GKPSPRPKFP SFHFPSTFTL PLGMIFHPRS 
421:	HFLYVYGSQI WVSMDGGNTF EMLCNLFSHH VTKTSNSFYT SDIVFIVEDG RILTTKAGLT 
481:	TYSELGILKD AIFTLYYDQL GYIHKLTPEN FDAGSKLLGH GNSGSIFGKR PDLGFEAILV 
541:	PQYISTNEMY FFAHVPLTMP TNIQWKKRFK TIHLGKTIEF SKTGLANIKN VYMHKTEPVG 
601:	FQTSIHTEII VPFGIENSKD SPCLLSDLEI TYSGKLYYTI KLLSKNPLHE LKSTDVEKSV 
661:	LIPGYSSFLI MNITDKWTAS ALATMPQAIK SNLKFLTGSW FLYNFGTAGG RKWSISTRQC 
721:	NYWIQQDSLD FMSLNLVKYI DVGNTIDFQF KIIPKAMSTF PIPPVSMVVG NPGLVEVKTQ 
781:	GVFDLNENYY LDIHVSGRFF QKGSTSIALV LWEGSSKCYA ITLLPTIKSS CSYLRTMHHT 
841:	PGRHIPPEDW ISGVHKDSQG FNMIKTLPIN YRPPSHMGIS IPLTDNFYHA DPSKPIPRNQ 
901:	FHKSKETGKY KQCANVTSRA MCNCSEHQKF SHAVAFSDCK EKVHRFKFPV TQYPVVLEIF 
961:	NERDKISAEP PYLVTMTEVN MRKNWQLKHN EPENVKKMKH YLEPLLKTPV YNPLGLNLTI 
1021:	QGSELFHFKV SVVPGVSFCE LSEEFQIYVD EVPLPFPGHA LIAVATSVVL GVLIFIAFVF 
1081:	QLRNIHPLKA LKKSIRGNPG LTSSTTVSS

1.A.1.19.3
Alkalinization-activated, Ca²⁺-selective cation channel of sperm 1, CatSper1, required for male fertility and the hyperactivated motility of spermatozoa. These channels require auxiliary subunits, CatSper β, γ and δ for activity (Chung et al., 2011; Liu et al., 2007).

Cross database links:

Gene Ontology

References (4)

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1.A.1.19.3 Alkalinization-activated, Ca2+-selective cation channel of sperm 1, CatSper1, required for male fertility and the hyperactivated motility of spermatozoa. These channels require auxiliary subunits, CatSper β, γ and δ for activity (Chung et al., 2011; Liu et al., 2007).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

1.A.1.19.3
Alkalinization-activated, Ca²⁺-selective cation channel of sperm 1, CatSper1, required for male fertility and the hyperactivated motility of spermatozoa. These channels require auxiliary subunits, CatSper β, γ and δ for activity (Chung et al., 2011; Liu et al., 2007).