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3.D.7.2.1 Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.
Accession Number:	O67095
Protein Name:	HydB aka MbhS2
Length:	349
Molecular Weight:	38187.00
Species:	Aquifex aeolicus [63363]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hydron

RefSeq:	NP_213658.1
Entrez Gene ID:	1193637
Pfam:	PF01058
BioCyc:	AAEO224324:AQ_965-MONOMER
KEGG:	aae:aq_965
Gene Ontology GO:0009375 C:ferredoxin hydrogenase complex GO:0051539 F:4 iron, 4 sulfur cluster binding GO:0008901 F:ferredoxin hydrogenase activity GO:0008137 F:NADH dehydrogenase (ubiquinone) activity GO:0048038 F:quinone binding GO:0055114 P:oxidation reduction
References (1) [1] “The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.” Deckert G.et.al. 9537320

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MESLYEIFKR KGYSRRDFLK FSLAVSAFLG LPPSLYPKVA QALEKKEKPV VIWLEFQDCA 
61:	GCSESFIRST TLLPTEVLLD YISLEYHETL MAPSGFYAEE AREEAIKKYK GKYVLVVEGS 
121:	PTPADGGVYC TVGGKSSVDI LRETAEHAAF VIAVGSCASW GGIPKASPNP TGAVPVYEIV 
181:	KDKPVVNVPG CPPIGDVMVA TIVHFLALGK LPPLDELGRP KQFYGETIHD RCYRRAFYNS 
241:	GQFAESFDDE KARKGYCLYK LGCKGPITRN ACASMRWNGG LSFPIQSGHP CFGCSEPDFW 
301:	DRGFIYNPLS VMEGYSGISD TLKGVGIGAA VGIGIGVLNK LINKKKEEK

3.D.7.2.1
Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.D.7.2.1Membrane-bound H2 oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.D.7.2.1
Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.