| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.C.112.1.1 | Cubozoan toxin, CaTX-A of 463 aas. This toxin has potent hemolytic activity, is lethal to crayfish. causes cutaneous inflammation in humans, and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells (Nagai et al. 2000; Brinkman and Burnell 2009). | Eukaryota |
Metazoa | CaTX-A of Carybdea alata |
|
1.C.112.1.2 | Toxin A of 454 aas; causes cardiiovascular and cytotoxic effects (Brinkman et al. 2014). | Eukaryota |
Metazoa, Cnidaria | Toxin A of Chironex fleckeri |
|
1.C.112.1.3 | Toxin TX1 of 486 aas and 2 - 4 N-terminal α-helical TMSs, possibly with up to 15 C-terminal transmembrane β-strands (Law 2018). | Eukaryota |
Metazoa, Cnidaria | Toxin TX1 of Aurelia aurita |
|
1.C.112.1.4 | C. fleckeri toxin-1 (CfTX-1) of 456 aas, one of the two most abundant proteins found in the nematocysts of the box jellyfish Chironex fleckeri. One or more of the 5 possible α-helical TMSs may be involved in pore-formation. May be similar to pore-forming insecticidal delta-endotoxins Cry1Aa, Cry3Bb and Cry3A (Brinkman and Burnell 2007). The transmembrane region(s) in CfTX-1 have been predicted on the basis of the behavior of peptides corresponding in sequence to two regions (Andreosso et al. 2018). | Eukaryota |
Metazoa, Cnidaria | CfTX-1 of Chironex fleckeri (Box jellyfish) |
|
1.C.112.1.5 | Toxin B precursor, TX-B, of 461 aas and 2 - 4 N-terminal TMSs and up to 15 C-termnal β-strands (Tibballs et al. 2011) . | Eukaryota |
Metazoa, Cnidaria | TXB of Chironex fleckeri (Box jellyfish) |
|
1.C.112.1.6 | Toxin CaTx-A of 446 aas. | Eukaryota |
Metazoa | CaTx-A of Exaiptasia pallida
|
|
1.C.112.1.7 | Uncharacterized toxin of 420 aas. | Eukaryota |
Metazoa, Mollusca | UP of Crassostrea gigas (Pacific oyster) (Crassostrea angulata) |
|
1.C.112.1.8 | Uncharacterized protein of 292 aas and 2 - 4 TMSs. | Eukaryota |
Metazoa, Cnidaria | UP of Stylophora pistillata |
|
1.C.112.1.9 | CrTx-A cytotoxin of 450 aas with 4 probable TMSs, one at the N-terminus, two at about residue110, and a fourth at about residue 230. It has potent hemolytic activity and is lethal to mice and crayfish (Nagai et al. 2000). It causes cutaneous inflammation in humans and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells. | None |
Metazoa, Cnidaria | CrTx-A of Carybdea rastonii (Box jellyfish) |