| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.143.1.1 | Transmembrane protein 132A, TMEM132A, of 1032 aas and 2 TMSs, N-terminal and near the C-terminus. It may play a role in embryonic and postnatal
development of the brain. Increased resistance to cell death is induced by
serum starvation in cultured cells. It regulates cAMP-induced GFAP gene
expression via STAT3 phosphorylation (Sanchez-Pulido and Ponting 2018). It may play a role in Lowe syndrome (LS) (Liu et al. 2020Liu et al. 2020). | Eukaryota |
Metazoa, Chordata | TMEM132A of Homo sapiens |
|
8.A.143.1.2 | Transmembrane protein 132E, TMEM132E of 1610 aas and 2 - 4 TMSs. | Eukaryota |
Metazoa, Arthropoda | TMEM132E of Danaus plexippus plexippus |
|
8.A.143.1.3 | Uncharacterized protein of 1176 aas and 1 TMS near the C-terminus. | Eukaryota |
Metazoa, Annelida | UP of Helobdella robusta |
|
8.A.143.1.4 | Uncharacterized protein of 1948 aas and 2 TMSs, one at the N-terminus, and one near the C-terminus. | Eukaryota |
Metazoa, Platyhelminthes | UP of Opisthorchis viverrini |
|
8.A.143.1.5 | TMEM132e of 1074 aas and 2 TMSs. Ion channel function for the α9α10 nicotinic acetylcholine receptor (1.A.9.1.22) requires an auxiliary subunit, which can be transmembrane inner ear (TMIE; TC# 8.A,116) or TMEM132e. Both of these single-pass transmembrane proteins are enriched in hair cells and underlie nonsyndromic human deafness (Gu et al. 2020). | Eukaryota |
Metazoa, Chordata | TMEM132e of Homo sapiens |