TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.39.1.2
OCT plasmid-encoded AlkL outer membrane cation-selective porin, (probably transports alkanes) (van Beilen et al., 1992).  Has been used for the uptake of dodecanoic acid methyl ester (DAME) in E. coli for the production of  12-aminododecanoic acid methyl ester (ADAME), a building block for the high-performance polymer Nylon 12 (Ladkau et al. 2016).

Accession Number:Q00595
Protein Name:AlkL
Length:230
Molecular Weight:24992.00
Species:Pseudomonas oleovorans [301]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate cations, Dodecanoic acid methyl ester

Cross database links:

Pfam: PF03922   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (1)

[1] “DNA sequence determination and functional characterization of the OCT-plasmid-encoded alkJKL genes of Pseudomonas oleovorans.”  van Beilen J.B.et.al.   1453953

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSFSNYKVIA MPVLVANFVL GAATAWANEN YPAKSAGYNQ GDWVASFNFS KVYVGEELGD 
61:	LNVGGGALPN ADVSIGNDTT LTFDIAYFVS SNIAVDFFVG VPARAKFQGE KSISSLGRVS 
121:	EVDYGPAILS LQYHYDSFER LYPYVGVGVG RVLFFDKTDG ALSSFDIKDK WAPAFQVGLR 
181:	YDLGNSWMLN SDVRYIPFKT DVTGTLGPVP VSTKIEVDPF ILSLGASYVF