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3.D.7.2.1 Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.
Accession Number:	O67092
Protein Name:	HydA aka MbhL2
Length:	564
Molecular Weight:	64738.00
Species:	Aquifex aeolicus [63363]
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hydron

RefSeq:	NP_213655.1
Entrez Gene ID:	1193634
Pfam:	PF00374
BioCyc:	AAEO224324:AQ_960-MONOMER
KEGG:	aae:aq_960
Gene Ontology GO:0008901 F:ferredoxin hydrogenase activity GO:0016151 F:nickel ion binding GO:0055114 P:oxidation reduction
References (1) [1] “The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.” Deckert G.et.al. 9537320

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKRVVVDPVT RIEGHLRIEA EVKDGKITKA YSSGTMVRGI EIILKGRDPR EAWAFAQRIC 
61:	GVCTTVHAIA SVRAVEDALS INVPVNASLL RKLIIGTIFV HDHVVHFYHL HLLDWVNPVQ 
121:	ALKADPYETS RLAQSLSNYE KSTPGYFREV QKKIKQQVER GQLGIFNKGY WNHPEYKLPP 
181:	ELNLMLIAHY LDALDWQTRI VQVHTIIGGK NPHPNFAVGG MAAPINPESD TAINMEKLGR 
241:	IKTLIDEMYD FTVKVYLPDI KVLGKYYKDW FFKGEGLGNF LVLGEPEKDS WREGKWFIPP 
301:	TFIKGRNLKD FEEVNINEVK EYVTHSWYKY SVGDDKPLHP WEGETNLNYT GPKPPYEYLN 
361:	VEGKYSWLKA PRYKDYSVEV GPLSRILALY ARDMYGIREE VEKHLKEMDV PFEGMFSTMG 
421:	RTFARALETK LYSFSMKNWF SELMENVKKG NYDVFNPEKW EPSTWPKETK GVGFMEAPRG 
481:	SLSHWVHIKD GKLENYQAVV PTTWNASPRD AKGNPSAYEA SLVGHSLHNP KEPVEILRTI 
541:	HSFDPCLACA VHLYGDEEME IRVV

3.D.7.2.1
Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.D.7.2.1Membrane-bound H2 oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

3.D.7.2.1
Membrane-bound H₂ oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC.