| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
2.A.126.1.1 | Tmemb_14 family protein of 4 TMSs. Show some sequence similarity with 2.A.7.26.3 | Bacteria |
Chlamydiota | Tmemb_14 protein of Prarchlamydia acanthamoebae |
|
2.A.126.1.2 | Uncharacterized protein of 105 aas | Eukaryota |
Discosea | UP of Acanthamoeba castellanii |
|
2.A.126.1.3 | Uncharacterized protein of 104 aas | Bacteria |
Cyanobacteriota | UP of Anabaena cylindrica |
|
2.A.126.1.4 | Uncharacterized protein of 102 aas | Eukaryota |
Evosea | UP of Dictyostelium discoideum |
|
2.A.126.1.5 | Uncharacterized protein of 111 aas | Eukaryota |
Metazoa, Arthropoda | UP of Bombyx mori |
|
2.A.126.1.6 | Uncharacterized protein of 114 aas and 4 TMSs, TMEM14DP or TMEM14D. | Eukaryota |
Metazoa, Chordata | UP of Homo sapiens |
|
2.A.126.1.7 | Uncharacterized protein of 166 aas with 4 TMSs and an N-terminal hydrophilic extension | Eukaryota |
Rhodophyta | UP of Galdieria sulfuraria |
|
2.A.126.1.8 | Tmem_14 protein of 110 aas | Eukaryota |
Fungi, Ascomycota | UP of Candida albicans |
|
2.A.126.1.9 | Uncharacterized protein of 104 aas | Eukaryota |
Fungi, Ascomycota | UP of Chaetomium globosum |
|
2.A.126.1.10 | Uncharacterized protein of 116 aas | Eukaryota |
Kinetoplastida | UP of Trypanosoma brucei |
|
2.A.126.1.11 | Uncharacterized protein of 105 aas and 4 TMSs | Eukaryota |
Fungi, Ascomycota | UP of Naumovozyma dairenensis (Saccharomyces dairenensis) |
|
2.A.126.1.12 | Uncharacterized protein of 116 aas | Bacteria |
Planctomycetota | UP of Isophaera pallida |
|
2.A.126.1.13 | Uncharacterized protein of 105 aas and 4 TMSs | Eukaryota |
Euglenozoa | UP of Trypanosoma vivax |
|
2.A.126.1.14 | Putative MDR efflux pump of 153 aas and 4 TMSs | Eukaryota |
Viridiplantae, Streptophyta | Putative porter of Zea mays (Maize) |
|
2.A.126.1.15 | Uncharacterized protein of 125 aas and 4 TMSs | Bacteria |
Cyanobacteriota | UP of Nostoc punctiforme |
|
2.A.126.1.16 | Chloroplast fatty acid export 2 protein FAX2 of 240 aas and 4 TMSs. | Eukaryota |
Viridiplantae, Streptophyta | FAX2 of Arabidopsis thaliana |
|
2.A.126.1.17 | Uncharacterized protein of 129 aas | Eukaryota |
Apicomplexa | UP of Babesia equi |
|
2.A.126.1.18 | Transmembrane Protein 14C (TMEM14C) of 112 aas and 4 TMSs. It is a mitochondrial porphyrin (protoporphyrinogen) transporter, essential for haem biosynthesis. It is an SF3B1 splicing target (Steensma et al. 2021). | Eukaryota |
Metazoa, Chordata | TMEM14C of Homo sapiens |
|
2.A.126.1.19 | TMEM14A of 99 aas and 4 TMSs. It inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in the apoptotic signaling pathway (). It inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of the mitochondrial membrane potential (Woo et al. 2011). | Eukaryota |
Metazoa, Chordata | TMEM14A of Homo sapiens |
|
2.A.126.1.20 | TMEM14B of 114 aas and 4 TMSs. It is a primate-specific protein involved in cortical expansion and folding in the developing neocortex. It may drive neural progenitor proliferation through nuclear translocation of IQGAP1, which in turn promotes G1/S cell cycle transitions (Liu et al. 2017). | Eukaryota |
Metazoa, Chordata | TMEM14B of Homo sapiens |
|
2.A.126.2.1 | Uncharacterized protein of 120 aas | Eukaryota |
Viridiplantae, Chlorophyta | UP of Micromonas pusilla |
|
2.A.126.2.2 | Uncharacterized protein of 220 aas with 4 TMSs and an N-terminal hydrophilic extension | Eukaryota |
Viridiplantae, Streptophyta | UP of Capsella rubella |
|
2.A.126.2.3 | Uncharacterized protein of 120 aas and 4 TMSs | Eukaryota |
Viridiplantae, Chlorophyta | UP of Chlorella variabilis (Green alga) |
|
2.A.126.2.4 | Plastid fatty acid export protein 1, FAX1, of 226 aas and 4 TMSs with an N-terminal hydrophlic domain (Li et al. 2015). | Eukaryota |
Viridiplantae, Streptophyta | FAX1 of Arabidopsis thaliana |